Fraction of Inspired Oxygen

Expressed as a percentage or a decimal. The air we breathe (room air) contains 21% oxygen. Room air FiO2 is expressed at 21% or 0.21. Below is a chart comparing the FiO2 of common oxygen delivery methods.

Nasal Cannula at 2 lpm28%
Nasal Cannula at 4 lpm36%
Nasal Cannula at 6 lpm44%
Non-Rebreather at 12-15 lpm80-100%
BVM at 15 lpm95-100%
FiO2 of oxygen delivery

The most common strategy for determining FiO2 with a vented patient is to start with 100% and titrate down from there to maintain goal SpO2 and PaO2.